Read e-book online Annals of Oncology: Official Journal of the European Society PDF

By Brian L. Samuels, John E. Ultmann (auth.), John E. Ultmann, Brian L. Samuels (eds.)

ISBN-10: 1489972943

ISBN-13: 9781489972941

ISBN-10: 1489973052

ISBN-13: 9781489973054

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Extra resources for Annals of Oncology: Official Journal of the European Society for Medical Oncology

Sample text

The clinical investigators of the recent past (Peters, Kaplan, Smithers, Rappaport, Lukes, De Vita, Bonadonna, and others) deserve great credit for transforming Hodgkin's disease from a usually fatal disease to a highly curable one. Many thousands of patients have lived normal lives, many of them parenting normal children, as a result of these investigators' efforts. But we cannot be satisfied. The treatment required for high cure rates remains empirical, difficult, and costly. Specific therapy based on the knowledge of the cause and pathogenesis of the disease must be the goal of investigators, and it is realistic to believe that goal can be achieved during the next decade.

The documentation of areas of bone marrow infiltrated with HD by quantitative MR imaging in patients with refractory lymphoma is clinically important, as only patients with noninvolved bone marrow are suitable for procedures such as autologous bone marrow transplantation, and alternative means of dose escalation exist for patients with involved marrow. Quantitative MR imaging may be a complementary technique to bone marrow biopsy in assessing bone marrow status when the presence of bone marrow involvement limits or dictates therapeutic options.

And (4) How closely are the Ki-1 + anaplastic large-cell (ALC) lymphomas related to Hodgkin's disease? The nature of Hodgkin and Reed-Sternberg (HRS) cells Significance of IgG-l

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Annals of Oncology: Official Journal of the European Society for Medical Oncology by Brian L. Samuels, John E. Ultmann (auth.), John E. Ultmann, Brian L. Samuels (eds.)


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